Deconvolution of Complex DNA Repair (DECODR): Establishing a Novel Deconvolution Algorithm for Comprehensive Analysis of CRISPR-Edited Sanger Sequencing Data
نویسندگان
چکیده
منابع مشابه
DNA sequencing and parametric deconvolution
One of the key practices of the Human genome project is Sanger DNA sequencing. Its data analysis part is called base-calling, which attempts to reconstruct target DNA sequences from fluorescence intensities generated by sequencing machines. In this paper, we present our modeling framework of DNA sequencing, in which a base-calling scheme arises naturally. A large portion of DNA sequencing error...
متن کاملBeamforming-deconvolution: A novel concept of deconvolution for ultrasound imaging
In ultrasound (US) imaging, beamforming is usually separated from the deconvolution or some other post-processing techniques. The former processes raw data to build radio-frequency (RF) images while the latter restore high-resolution images, denoted as tissue reflectivity function (TRF), from RF images. This work is the very first trial to perform deconvolution directly with raw data, bridging ...
متن کاملA novel deconvolution beamforming algorithm for virtual phased arrays
Beamforming techniques using phased microphone arrays are one of the most common tools for localizing and quantifying noise sources. However, the use of such devices can result in a series of well-known disadvantages regarding, for instance, their very high cost or transducer mismatch. Virtual Phased Arrays (VPAs) have been proposed as an alternative solution to prevent these difficulties provi...
متن کاملDeconvolution Analysis of FMRI Time Series Data
Program dDeconvolve was developed to provide deconvolution analysis of FMRI time series data This has two primary applications estimation of the system impulse response function and multiple linear regression analysis of time series data Given the input stimulus function s and the measured FMRI signal data program dDeconvolve rst estimates the impulse response function s the impulse response fu...
متن کاملEfficient Deconvolution Algorithm
This thesis describes the design of a new deconvolution approach known as Efficient Deconvolution algorithm so that reconstruction image will be free from both blur and noise. This algorithm comprises two steps, a global blur compensation using generalized Wiener filter, followed by a pure local denoising algorithm using dual-tree complex wavelet transform (DT-CWT). The main advantage of this d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The CRISPR Journal
سال: 2021
ISSN: 2573-1599,2573-1602
DOI: 10.1089/crispr.2020.0022